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This is because of their anti-melanogenic effects, which prevent skin pigmentation and lead to skin lightening

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Additionally, AMDs pathogenesis involves the loss of RPE-derived VEGF signaling and defenestration of usually high permeable choriocapillaries in atrophied RPE areas, which disrupts retinal permeability [440, 441]

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While arGSTs were shown to catalyse the nucleophilic transfer of the tripeptide glutathione (GSH) onto the model substrate 1-chloro-2,4-dinitrobenzene (CDNB) ( 5 ) in vitro, such GSH conjugates with anthocyanins ( 1 ) were never observed in vitro or in planta 19,31,32